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Professor Rupert Leong is the Director of Endoscopy at Concord Hospital, Sydney. He conducts private endoscopy services at both Macquarie University Hospital (9812 3880) and Sydney Specialist Medical Centre (Level 11 501 George St, Sydney; and Central Sydney Private Hospital, 8378 6666). 

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Consultancy Bio

Professor Rupert Leong serves as the Director of Endoscopy and Head of the Inflammatory Bowel Disease Services at Concord Hospital. Additionally, he holds the position of Head of GI Services and Chair of the Medical Advisory Committee at Central Sydney Private Hospital. He oversees a private IBD Clinic and the IBD research group at Macquarie University Hospital. He is Professor of Medicine at University of Sydney and Macquarie University, Sydney Australia. After completing gastroenterology and clinical immunology training at the University of Western Australia, he pursued an additional two years of interventional endoscopy fellowship training at the Prince of Wales Hospital in Hong Kong, where he held the esteemed position of Amy and Athelstan Saw Research Fellow. His doctoral thesis, "Inflammatory Bowel Diseases in the Chinese Population," earned him recognition as a Researcher on the Rise by both the Gastroenterological Society of Australia and the American Gastroenterological Association Fellowship for his exceptional research contributions. Subsequently, he was granted an Australian NHMRC Career Development Fellowship (level 2 clinical), a distinction awarded to only five individuals that year.

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Prof Leong has published over 300 (h index 66) high quality scientific journals publications in Nature Reviews, Gastroenterology, Gut, Gastrointestinal Endoscopy, Lancet Gastroenterology & Hepatology and Endoscopy. Amongst these are senior authorships of national and international consensus clinical practice guidelines in both Australia and in Asia. Guidelines on the management of acute severe ulcerative colitis, therapeutic drug monitoring of IBD biological agents, regulation and use of faecal microbiota transplantation were published in peer-reviewed journals, have been widely cited and endorsed by national and international gastroenterological societies. Rupert chairs the Medical Advisory Council at Central Sydney Private Hospital and is an executive director on the boards of IBD Sydney and Central Sydney Private Hospital. He is an associated editor of Therapeutic Advances in Gastroenterology and serves on the international editorial boards of the American Journal of Gastroenterology, Alimentary Pharmacology and Therapeutics and Gastrointestinal Endoscopy.

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Prof Leong has been consulted by professional agencies on many occasions including philanthropic, incubator investment, government, funding agencies and pharmaceutical industry partners. He was invited to comment on submissions to the PBAC including direct contact via video-link and letters of recommendations for inclusion to list new medications. He was engaged by the Pharmaceutical & Technology Clinical Management Association of South Africa to review chronic disease management that might influence national funding policies. In 2024 he was engaged to present to South African funding bodies alternative treatment algorithms to treat inflammatory bowel diseases using real world evidence.  

Gastroscopy

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Gastroscopy is the visualisation of the oesophagus, stomach and duodenum using a flexible telescope. This is a quick and simple procedure performed under sedation, typically administered by an anaesthetist. The procedure takes approximately 15 minutes. 

The indications of gastroscopy includes difficult-to-manage or chronic acid reflux, stomach discomfort, iron deficiency or anaemia, diarrhoea, exclusion of coeliac disease or gastric cancer. Family history of upper gastrointestinal cancers may require gastroscopy. General practitioners may refer you for gastroscopy directly (Direct Access Gastroscopy).  

Colonoscopy

Colonoscopy is the visualisation of the large bowel and the tip of the small bowel (terminal ileum) using a flexible telescope. This is a quick and simple procedure performed under sedation, typically administered by an anaesthetist. The procedure takes approximately 20 minutes. 

The indications of colonoscopy includes investigation of abdominal discomfort, iron deficiency or anaemia, diarrhoea, blood in the stools or on toilet paper, weight loss or concern regarding bowel cancer and inflammatory bowel diseases. Screening colonoscopy may be appropriate. General practitioners may refer you for gastroscopy directly (Direct Access Colonoscopy).  

Polypectomy

Polypectomy is the removal of polyps in the bowel to prevent them for progressing onto bowel cancer. This is achieved using electrocautery and rarely complicated by bleeding or bowel perforation. 

Needle Knife Stricturotomy, Balloon Dilatation 

These are techniques that open up strictures in Crohn's disease or strictures that complicate ileopouch anal anastomoses in ulcerative colitis. 

rupertleong.com

Corona virus COVID-19 

Overall the risk is low. You are more at risk of common cold and influenza (which you should be immunized against via your GP). See risk stratification according to the BSG (scroll down).

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For IBD Patients on immunosuppression, PAXLOVID is an anti-viral treatment available via your GP to be given within 5 days from the onset of COVID-19 symptoms. Please check with your GP. 

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Long COVID 

Abstract

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is associated with a range of persistent symptoms impacting everyday functioning, known as post-COVID-19 condition or long COVID. We undertook a retrospective matched cohort study using a UK-based primary care database, Clinical Practice Research Datalink Aurum, to determine symptoms that are associated with confirmed SARS-CoV-2 infection beyond 12 weeks in non-hospitalized adults and the risk factors associated with developing persistent symptoms. We selected 486,149 adults with confirmed SARS-CoV-2 infection and 1,944,580 propensity score-matched adults with no recorded evidence of SARS-CoV-2 infection. Outcomes included 115 individual symptoms, as well as long COVID, defined as a composite outcome of 33 symptoms by the World Health Organization clinical case definition. Cox proportional hazards models were used to estimate adjusted hazard ratios (aHRs) for the outcomes. A total of 62 symptoms were significantly associated with SARS-CoV-2 infection after 12 weeks. The largest aHRs were for anosmia (aHR 6.49, 95% CI 5.02-8.39), hair loss (3.99, 3.63-4.39), sneezing (2.77, 1.40-5.50), ejaculation difficulty (2.63, 1.61-4.28) and reduced libido (2.36, 1.61-3.47). Among the cohort of patients infected with SARS-CoV-2, risk factors for long COVID included female sex, belonging to an ethnic minority, socioeconomic deprivation, smoking, obesity and a wide range of comorbidities. The risk of developing long COVID was also found to be increased along a gradient of decreasing age. SARS-CoV-2 infection is associated with a plethora of symptoms that are associated with a range of sociodemographic and clinical risk factors.

Subramanian A,et al. Nat Med. 2022 Aug;28(8):1706-1714

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